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KMID : 0360419770130020061
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Korean Journal of Pharmacology
1977 Volume.13 No. 2 p.61 ~ p.65
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Clinical Trials of Cofrel for Cough in Infants and Young Children
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Abstract
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We tried Cofrel?? (Pyrexyl?? 1-(2-benzyl phenoxy)-2-piperidino-propane phosphate) which is non-narcotic, to evaluate its clinical effect on cough due to respiratory tract diseases-35 cases.
1) Thirty two cases amoag 35 cases disclosed remarkable effectiveness (91.4% of efficacy)
2) It was almost equally effective in dry cough, productive cough and barking cough.
3) Speed of response was very rapid in 21 cases(60.0%) moderately rapid in 12 cases(34.3%).
4) Palatability were excellent in all cases and side effect was not observed.
It is very difficult to evaluate effectiveness of anti-tussive drug. However, we concluded that Cofrel is a quite effective medicament for cough in respiratory diseases in children.
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